Events and meetings
The project was kicked off by consortium members in June 2019 at the University of Eastern Finland (the upper photo). On October 10 2023 the investigators of the TUBE consortium presented their key findings and policy recommendations in stakeholder work shop held in Brussels. The General Assembly also held the last meeting a day after.
Ultrafine particles and health information for regulators and policy developers
In this workshop, investigators of the TUBE (Transport derived Ultrafines and the Brain Effects) consortium and other related projects presented their key findings for stakeholders and how this could be input for policy. It was aimed to increase the understanding of the (health) impact of the different transport modes through monitoring, detection and modelling of emissions in the existing road vehicle fleet as well as ships and aircraft in different source environments. In addition, data for risk assessment from air pollutants from different transport modes and identification of cost-effective reduction measures was showed. Moreover, technical evidence was provided to assess gaps in current regulation of vehicles, fuels and air quality to promote better health.
The 1st TUBE – Stakeholder Workshop has been organized in Prague, June 1, 2022. This project midterm milestone featured project progress and initial achievements explained to interested stakeholders, collecting feedback to be used for future project implementation.
Group picture TUBE-partners and at the same time, the hybrid TUBE Executive Board meeting was held on May 31, 2022.
Pictures: Workshop in progress, featuring Dr. Maurizio Maggiore, Senior Expert at European Commission, Directorate General for Research and Innovation, Surface Transport Unit
Group picture TUBE-partners and at the same time, the hybrid TUBE Executive Board meeting was held on May 31, 2022.
Kick-Off Meeting:
2019 – 16.-17/6/2019, University of Eastern Finland, Kuopio campus, Finland
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General Assembly Meetings:
2021 – 26/1/2021, Web-meeting (Zoom)
2022 – 5/4/2022, Web-meeting (Zoom)
2023 – 11/10/2023, face-to-face, Brussels
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Executive Board Meetings:
2019
2019 – 17/6/2019, Kuopio, Finland
2020
2020 – 18/2/2020, Amsterdam (Schiphol Airport Hilton), The Netherlands
2020 – 4/5/2020, Web-meeting (Lifesize Cloud)
2021
26/1/2021, Web-meeting (Zoom)
7/6/2021, Web-meeting (Zoom)
29/10/2021, Web-meeting (Zoom)
2022
31/5/2022, Prague, Czech Republic
15-17/11/2022 Venice
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External Advisor Board Meetings:
2020 – 2/6/2020, Web-meeting (Lifesize Cloud)
2021 – 7/6/2021, Web-meeting (Zoom)
2022 – 5/5/2022 Web-meeting (Zoom)
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Review Meetings:
RV1 – 7/12/2020, Web-meeting (Webex)
RV2 – 24/5/2022, Web-meeting (Zoom)
RV3 – 13/12/2023, Web-meeting (Zoom)
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Partner web-meetings:
Continuously
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This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 814978.
TUBE organized an active seminar programme for both consortium members and research students. We feature speakers from all disciplines of TUBE research and encourage active participation from those present.
Multidisciplinary Climate and Health Research at the University of Eastern Finland – Seminar, May 10, 2022, Kuopio campus
TUBE online Seminar / 5 March 17.2022
Topic:
Particle emissions in TUBE engine and vehicle measurement campaigns
-Effect of fuel on particle emissions of a diesel engine
-Particle emissions of the latest Euro 6 passenger cars in warm and cold conditions by Senior Scientist Dr. Anssi Järvinen, VTT, Finland
TUBE organizes an active seminar programme for both consortium members and research students. We feature speakers from all disciplines of TUBE research and encourage active participation from those present.
Multidisciplinary Climate and Health Research at the University of Eastern Finland – Seminar, May 10, 2022, Kuopio campus
Pictures: featuring Assoc. prof. Pasi Jalava and Prof. Tarja Malm
TUBE Seminar / 5
Date: March 17, 2022
Time: 14.00 CET
On-line event: Zoom
Topic: Particle emissions in TUBE engine and vehicle measurement campaigns
-Effect of fuel on particle emissions of a diesel engine
-Particle emissions of the latest Euro 6 passenger cars in warm and cold conditions
by Senior Scientist Dr. Anssi Järvinen, VTT, Finland
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TUBE & ADAIR Seminar
Date: December 7, 2021
Time: 16.00 CET (can be subject to changes)
On-line event: Zoom
Topic: Cognition and brain MRI in seemingly healthy young adults exposed to PM2.5. – Role of developmental neurotoxicity. Where are we standing? (by Professor Lilian Calderón-Garciduenas, University of Montana and Universidad del Valle de México)
Lilian Calderón-Garcidueñas knew she wanted to be a physician by the time she finished middle school and she started medical school at age 15. Her pathology and neuropathology training at the University of Toronto were followed by her neuropathology fellowship at Harvard University, her Chief Pathology resident position at the University of Massachusetts at Worcester and her first position as an Assistant professor at Northwestern University in Chicago. She earned an American Board in Anatomical Pathology and Neuropathology in 1981. Her interest for clinical environmental research took her back to Chapel Hill, North Carolina where she earned a PhD in Toxicology in 2001, followed by three years as a postdoctoral fellow in Environmental Pathology. She is now affiliated as a professor at the Dept of Biomedical and Pharmaceutical Sciences at The University of Montana.
Her interest in air pollution and clinical environmental research took her back to school at the University of North Carolina at Chapel Hill, where she earned a degree in Toxicology in 2001, followed by a PostDoc in Environmental Pathology at the UNC Gillings School of Global Public Health.
Prof Calderón-Garcidueñas is interested in the chronic effects of exposure to air pollutants both indoors and outdoors in clinically healthy children. A crucial aspect is the role of cytokine imbalance in the respiratory tract, and cardiovascular pathology and on systemic effects. In her most recent work, her team has described the development of quadruple aberrant protein pathology in the brains of children and young adult residents in Metropolitan Mexico City. The quadruple pathology includes Alzheimer hyperphosphorylated tau and beta amyloid, Parkinson alpha-synuclein, while the TAR DNA-binding protein 43 is seen in motor and non-motor neuronal groups. Interestingly, 99.5% of the 204 forensic autopsies in MMC residents ≤40y old had the AD hallmarks, 23% PD and 18% TDP-43 pathology in subjects with no extra-neural pathology. She emphasizes there is a common denominator, and the question to pursue is: are solid nanoparticles at the core of the problem? The problem is a serious one, >55% of the MMC young adults are cognitively impaired and in a recent work she showed an association between PTSD and pRBD, strengthening the possibility of a connection with misfolded proteinopathies in young urbanites.
More information: https://health.umt.edu/biomed/people/default.php?ID=1331
The TUBE-project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 814978.
The ADAIR project is funded under the 2019 JPCO-Fund call for Personalised Medicine under the grant number, JPND2019-466-037
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TUBE Seminar / 4
Date: November 4, 2021
Time: 15.00 CET (can be subject to changes)
On-line event: Zoom
– ‘Disease specific alterations in the olfactory mucosa of patients with Alzheimer’s disease’ (Riikka Lampinen, PhD student, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland)
– ‘Changes in DNA methylation profile in AD olfactory mucosa’ (Katerina Honkova, PhD student, Institute of Experimental Medicine, Prague, The Czech Republic)
– ‘Air pollutants impair hiPSC-microglial function’ (Henna Konttinen, PhD student, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland
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TUBE Seminar / 3
Date: September 9, 2021
Time: 17.00 CET
On-line event: Zoom
‘TRAPs and neurodevelopmental disorders (autism)’ (Prof. Anthony Wexler, Assoc. Prof. Jill Silverman and Liz Berg, PhD, from UCL Davis)
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TUBE Seminar / 2
Date: June 3, 2021
Time: 14.00 – 15.00 CET
On-line event: Zoom
‘Lung-deposited surface area ratio on size distribution of particulate matter’ (Jorge Vidal, MSc, Centro Mario Molina, Chile)
‘Characteristics and size of lung-deposited particles varies between high and low pollution traffic environments’ (Laura Salo, MSc, University of Tampere, Finland)
‘Chemical characterization of ambient particles in locations with contrasting emission sources’ (Luis Barreira, PhD, Finnish Meteorological Institute)
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TUBE Seminar / 1
Date: May 7, 2021
Time: 17.00 – 18.00 CET
On-line event: Zoom
‘Chronic exposure to ambient traffic-related air pollution promotes Alzheimer’s disease phenotypes in wildtype and genetically predisposed male and female rats’
Presented by: Pamela J. Lein, PhD, Professor of Neurotoxicology, Chair, Department of Molecular Biosciences, Director, UC Davis Counter ACT Center of Excellence, UC Davis School of Veterinary Medicine, Australia
and Keith J. Bein, PhD, Associate Professional Researcher Air Quality Research Center, Research Professor Center for Health and the Environment at U.C. Davis, Australia
TUBE Online Seminar /4, November 4, 2021
Topics:
– ‘Disease specific alterations in the olfactory mucosa of patients with Alzheimer’s disease’ (Riikka Lampinen, PhD student, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland)
‘Changes in DNA methylation profile in AD olfactory mucosa’ (Katerina Honkova, PhD student, Institute of Experimental Medicine, Prague, The Czech Republic)
‘Air pollutants impair hiPSC-microglial function’ (Henna Konttinen, PhD student, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland
TUBE Online Seminar /3 September 9, 2021
‘Topic:
TRAPs and neurodevelopmental disorders (autism)’ (Prof. Anthony Wexler, Assoc. Prof. Jill Silverman and Liz Berg, PhD, from UCL Davis)
TUBE Online Seminar /2 June 3, 2021
Topics:
‘Lung-deposited surface area ratio on size distribution of particulate matter’ (Jorge Vidal, MSc, Centro Mario Molina, Chile)
‘Characteristics and size of lung-deposited particles varies between high and low pollution traffic environments’ (Laura Salo, MSc, University of Tampere, Finland)
‘Chemical characterization of ambient particles in locations with contrasting emission sources’ (Luis Barreira, PhD, Finnish Meteorological Institute)